Phenotype and Response to PAMPs of Human Monocyte-Derived Foam Cells Obtained by Long-Term Culture in the Presence of oxLDLs

Phenotype and Response to PAMPs of Human Monocyte-Derived Foam Cells Obtained by Long-Term Culture in the Presence of oxLDLs

Ldl cholesterol-laden, foam macrophages represent probably the most attribute part of human atherosclerotic plaques. Persistent uptake of oxLDLs ends in accumulation of lipid our bodies contained in the cells and determines their phenotype and subsequent features. On this work, we describe the phenotype of human monocyte-derived foam cells obtained by differentiation within the fixed presence […]

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ITGA6+ Human Testicular Cell Populations Acquire a Mesenchymal Rather than Germ Cell Transcriptional Signature during Long-Term Culture

ITGA6+ Human Testicular Cell Populations Acquire a Mesenchymal Rather than Germ Cell Transcriptional Signature during Long-Term Culture

Autologous spermatogonial stem cell transplantation is an experimental method aimed toward restoring fertility in infertile males. Though efficient in animal fashions, in vitro propagation of human spermatogonia previous to transplantation has confirmed to be troublesome. A significant limiting issue is endogenous somatic testicular cell overgrowth throughout long-term tradition. This makes the tradition each inefficient and […]

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